The collection contains over 100 rare letters, autograph quotations, and photographs from 50 major figures in the American antislavery struggle, including several rare autographs from key British abolitionists. Many of the individuals noted provided selfless support, financially, morally, and wrote on behalf of the abolishment of the 'peculiar' institution of slavery. Some of the well-known abolitionists include Henry Ward Beecher, Blanche K. Bruce, William Channing, William Lloyd Garrison, Joshua R. Giddings, the Grimke sisters, Gerrit Smith, Thaddeus Stevens, Charles Sumner, and Lewis Tappan, one of the leading financial supporters of the Amistad Africans.

The collection contains photographs and newspaper clippings of these 50 prominent abolitionists.